Multiple-omics analysis of aggrephagy-related cellular patterns and development of an aggrephagy-related signature for hepatocellular carcinoma

Abstract Background Protein aggrephagy, a selected autophagy process response for degrading protein aggregates, plays a critical role in various cancers.However, its regulatory mechanisms and clinical implications in hepatocellular carcinoma (HCC) remain largely unexplored.Methods We integrated bulk RNA-seq data from TCGA and single-cell RNA sequen

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Compositional variability of Mg/Ca, Sr/Ca, and Na/Ca in the deep-sea bivalve Acesta excavata (Fabricius, 1779).

Acesta excavata (Fabricius, 1779) is a slow growing bivalve from the Limidae family and is often found associated with cold-water coral reefs along the European continental margin.Here we present the compositional variability of frequently used proxy elemental ratios (Mg/Ca, Sr/Ca, Na/Ca) measured by laser-ablation mass spectrometry (LA-ICP-MS) and

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